A study originally focusing on cancer has shown that amyloids — proteins typically linked to neurodegenerative diseases like ...

This feature is not only characteristic of classic neurodegenerative disorders but also of prion disorders and other amyloidosis ... APP and presenilin 1 developed tangles and Aβ plaques, and ...

Pathological hallmarks of AD include neuritic plaques (extracellular deposits of β-amyloid) and neurofibrillary tangles (intraneuronal deposits of insoluble hyperphosphorylated tau protein). These ...

Dental plaque is a sticky, colorless film that forms on teeth. It makes teeth "feel fuzzy" to the tongue and is most noticeable when you haven't brushed your teeth recently. Although dental plaque ...

Prion Protein (PrP) is a normal protein found in healthy cells, though its exact role is not yet clear. However, when this protein changes shape into a misfolded form, it becomes infectious and is ...

Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT Leeds, U.K. Astbury Centre for Structural ...

Image: public domain Audrey Hepburn and Marc Bolan will be commemorated with Blue Plaques in London later in 2025. Marc Bolan already has a few memorials in London, but will now get an official ...

Rex frontman Marc Bolan are among those to be recognised with blue plaques in London, English Heritage has announced. People whose creative achievements have helped shape the capital were the ...

Department of Chemical, Materials, and Industrial Production Engineering (DICMaPI), University of Naples Federico II, Naples 80125, Italy Interdisciplinary Research Centre on Biomaterials (CRIB), ...

The authors performed extensive coarse-grained molecular dynamics simulations of 140 different prion-like domain variants to interrogate how specific amino acid substitutions determine the driving ...

The National Prion Disease Pathology Surveillance Center (NPDPSC) is the only Center of its kind in the U.S., which coordinates autopsies and neuropathologic examinations of suspected prion disease ...