what is the computational implication of having multiple spines connecting to the same presynaptic bouton? What could be the advantage of having two distinct spines, which, on all accounts ...

Scale bars, 20 µm (left), 10 μm (right). (C) Airyscan images of the presynaptic boutons aroundα3 (left) and dendritic projections in the γ1 compartment (right). White squares in the right panels are ...

Conclusion: The post-MCAO dystrophic axonal segments are mostly swollen presynaptic structures or boutons. This type of post-stroke axonal injury is likely a result of the lack of support from ...

The biological fates of the key initiator of Alzheimer’s disease (AD), the amyloid precursor protein (APP), and a family of lipoprotein receptors, the low-density lipoprotein (LDL) receptor-related ...

Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the degeneration of both upper and lower motor neurons. Despite decades of research, we still to date lack a cure or disease ...

Clinical Physiology provides diagnostic methods to detect and evaluate dysfunction of various organs and systems in the body such as the heart, peripheral vessels, lungs, kidneys, gastrointestinal ...