News

BMJ4d
A phase I, open-label, multicentre, first-in-human study to evaluate safety, pharmacokinetics and efficacy of AMG 404, a PD-1 inhibitor, in patients with advanced solid tumours
The 480 mg Q4W dose was selected as the recommended phase II dose. AMG 404 serum exposure increased approximately dose proportionally. The objective response rate (80% CI) was 19.6% (15.7–24.1) for ...
Red Five on MSN4d
The Most Distinctive Clone Trooper Armors in the Galaxy!
Clone Troopers wore more than just standard Phase I and Phase II armor some had unique, customized, and highly specialized ...
Frontiers6d
Efficacy and safety of BVAC-C in HPV type 16- or 18–positive cervical carcinoma who failed 1st platinum-based chemotherapy: a phase I/IIa study
A swimmer plot is presented in Figure 2B. We combined the phase I data with the phase II study (Arm 1, BVAC-C cycle of 3) due to the absence of discernible differences in efficacy between the two ...