Critical limb ischemia (CLI) is associated with a higher risk of limb amputation and cardiovascular death. Dapagliflozin has shown great potential in the tre ...

Diabetes mellitus (DM) is accompanied by a series of macrovascular and microvascular injuries. Critical limb ischemia is the most severe manifestation of per ...

Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis ...

Background: Angiogenesis is integral for embryogenesis, and targeting angiogenesis improves the outcome of many pathological conditions in patients. TBX20 is a crucial transcription factor for ...

Severe skeletal muscle injuries are common and can lead to extensive fibrosis, scarring, and loss of function. Clinically, no therapeutic intervent ...

For laser Doppler perfusion imaging, the animals were anesthetized and measured under a Periscan PIM II imager (Perimed, Järfälla, Sweden). The readings of 3 individual measurements per mouse were ...

ABSTRACT Rats suffering from adjuvant arthritis (AA) were used to examine the effect of a static magnetic field (SMF) upon pain relief. Rats were divided into SMFtreated AA rats, non-SMF treated AA ...

Assessment of microvascular endothelial function has been performed using scanning laser Doppler flowmeter (Periscan system PIM II, Perimed AB, 780 nm red laser) with iontophoresis (0.1 mA for 60 ...

Objective— Peripheral arterial disease (PAD) can have severe consequences on patient mortality and morbidity. In contrast to approaches using growth factor administration or isolated cell ...