Net Loss: Net loss for the three months ended June 30, 2025, totaled $17.6 million, with non-cash stock-based compensation expense of $4.2 million, compared to $7.9 million for the same period in 2024 ...

Prof. Fang-Jen S. Lee's team at National Taiwan University has discovered that an intermediate cellular metabolism molecule, ...

This important study provides evidence for dynamic coupling between translation initiation and elongation that can help maintain low ribosome density and translational homeostasis. The authors combine ...

AI in Cancer Drug Discovery could prove paradigm shifting, but what challenges does it present? And how can they be avoided?

Creatine supplementation may improve cognitive performance and mood, offering insights into its role in muscle-brain ...

As the days grow shorter, many animals prepare for the approaching winter by suspending reproduction. Insects, for example, accumulate energy stores while halting ovarian development through a process ...

Together with the abundant GPCRs detected in choanoflagellates, the finding of nearly complete G protein signaling pathways suggests that choanoflagellates engage in metazoan-like G protein signaling.

A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...

Hepatocellular carcinoma (HCC), which accounts for up to 80% of cases of primary liver cancer, is typically diagnosed in an advanced stage, meaning a poor prognosis. Understanding what drives ...

GPCRs (G protein-coupled receptors), also known as 7 transmembrane domain receptors, are the largest receptor family in the human genome, with ≈800 members. GPCRs regulate nearly every aspect of human ...

The adenosine A2A receptor (A2AAR) belongs to the rhodopsin-like G protein-coupled receptor (GPCR) family, which constitutes the largest class of GPCRs. Partial agonists show reduced efficacy as co ...

Takeda G protein-coupled receptor 5 (TGR5) is a membrane receptor for bile acids that has been found to play an important role in various disease processes, such as inflammation, oxidative stress, and ...