G-protein-coupled receptor, a large family of cell surface receptors that transmit signals into cells. Biased signalling: The preferential activation of certain downstream signalling pathways over ...

This study presents compelling evidence that the denitrosylase SCoR2 regulates cardioprotective metabolic reprogramming in the heart following ischemia/reperfusion injury. The findings are supported ...

Company enters option agreement with JiKang Therapeutics to in-license novel APJ agonist antibody New composition of matter IP filed for ch ...

Learn about May 2025’s top biotech deals, featuring major collaborations in RNA interference technology, small molecules, and ...

Leitner studies how energy flows through molecules, especially in biological systems like protein complexes. Being named Foundation Professor includes a reward of $7,500 per year for three years to be ...

G protein–coupled receptors (GPCRs) are a protein superfamily comprising >800 members that regulate numerous cellular and physiologic responses. GPCRs represent the largest class of therapeutic ...

Engineering of TRPM8 channel to be activated by CHXOL and more sensitive to CHXOL.  FAYETTEVILLE, GA, UNITED STATES, May 30, 2025 /EINPresswire.com/ -- In a breakthrough advancement for neuroscience, ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

Chinese scientists have recently discovered that the Qinghai-Tibet Plateau acts as the only net greenhouse gas (GHG) sink region in China. The study, led by Wang Tao, a researcher from the Institute ...

ABCL635 specifically targets NK3R, a clinically validated G-coupled protein receptor (GPCR) expressed on kisspetin, neurokinin, and dynorphin (KNDy) neurons in the infundibular nucleus of the ...