The study is recruiting patients with documented PBC and moderate to severe itching, who can either be treatment-naïve or already receiving standard itch therapies like colestyramine and ...

GSK has announced positive headline results of its ongoing global Phase III clinical trial GLISTEN, which is evaluating the use of linerixibat in the treatment of adult patients with cholestatic ...

SSRIs, used to treat depression, sometimes ease itch in patients with PBC. Opioid antagonists, used to treat heroin overdoses, sometimes do the same. Cholestyramine, which soaks up bile acid (a ...

Advanz Pharma's bid to keep its Ocaliva treatment for rare liver disease primary biliary cholangitis (PBC) on the EU market has ended in failure. The European Commission revoked the conditional ...

3. Itches have their own nerve network Until recently we thought that itch and pain both shared the same pathways, but in 1997 a ground-breaking discovery revealed that the itch has its own ...