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For adults, the standard dose of doxycycline to treat a urinary tract infection is 100 milligrams (mg) taken by mouth twice a day. In children ages 8 and older, the dosage is based on body weight and ...

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The approval of gepotidacin (Blujepa; GSK) introduces the first new class of oral antibiotics for uncomplicated urinary tract infections (UTIs) in nearly 30 years.

Nitrofurantoin (immediate release 50 mg 4 times per day, or extended release 100 mg twice a day) for 5 days is first-line treatment for an uncomplicated UTI; trimethoprim–sulfamethoxazole (800 mg/160 ...

Abstract Sustained release matrix tablets of 100 mg losartan potassium HCl were fabricated with two release retarding polymers namely HPMC K100 M and affinisol by direct compression method. Nine trial ...

Priority Review status for GSK’s New Drug Application for gepotidacin was based on promising results from the Phase III EAGLE-2 and EAGLE-3 trials, which demonstrated non-inferiority to nitrofurantoin ...

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Abstract Dissolution tests evaluate the release of therapeutic agents in various dosage forms, acting as quality control tools to secure batch–batch equivalence and guides for formulation development ...