A new study reveals that the thalamus, long overshadowed by the cortex and hippocampus, plays a crucial role in shaping and ...

Instead, they saw that the activity was slightly different every time, and reasoned that these changes reflected synaptic plasticity. To understand what drives these constant changes in neuronal ...

Neuronal plasticity is a fundamental process in neuronal development and recovery from brain disorders. The Trophin lab focuses on the role of neurotrophic factors, particularly Brain-Derived ...

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) ...

Experiences cause the strength of these connections to change—a process called synaptic plasticity, which underlies learning ...

New research from the University of Chicago challenges long-held beliefs about how synaptic plasticity contributes to memory ...

In 1898, Camillo Golgi, an eminent Italian physician and pathologist, published a landmark paper on the structure of “nervous cells.” In addition to the organelle that still bears his name, the Golgi ...

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 ...

He went on to show that neuronal activity drives Fos expression, kickstarting the production of synaptic plasticity-related genes and leading to long-term changes in connectivity. Fos acts on ...

BDNF is the brain’s most abundant neurotrophic factor, playing a key role in neuronal survival and synaptic plasticity through the activation of the transcription factor CREB, which is essential for ...