Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, and novel biomarkers are needed. We applied mass-spectrometry-based peptidomic analysis in cerebrospinal fluid (CSF) ...

Women with pregnancies after a systemic sclerosis diagnosis face higher risks for adverse pregnancy outcomes, with some risks also higher in prediagnosis pregnancies.

Menopause status, especially early menopause, impacts systemic sclerosis presentation, increasing risks for vascular and pulmonary involvement, according to a multicenter analysis of over 1,500 women.

Fenebrutinib was well tolerated and exerted an early, robust, and sustained effect of limiting new focal brain lesions. Further studies are needed to better characterise the safety and efficacy of ...

Background Limited data are available on the global rates of paediatric multiple sclerosis. Here, we report on the estimated worldwide prevalence of paediatric MS. Methods We included paediatric ...

I’m sure I’m not the only person who secretly likes a one-star review. It’s awful to get one yourself (and I have, several times), but I have to admit that there is a nasty kind of pleasure to be had ...

These are not anomalies. 3 These racial disparities are systemic signals of how social and economic instability erodes maternal health long before a crisis begins.

Objectives Cardiopulmonary involvement (CPI) is a major cause of morbidity and mortality in systemic sclerosis (SSc). The 6 min walk test (6MWT) is widely used to assess functional capacity, but its ...

Prostate cancer (PCa) is one of the most common cancers in males, and clinically significant PCa (csPCa) is one of the leading causes of death worldwide. Multi-parametric MRI (mp-MRI) has gained ...

The safety issues of MRI contrast agents in clinical practice have raised significant concerns, which can lead to adverse effects such as nephrogenic systemic fibrosis and metal deposition in the ...