Early detection and new biomarkers are changing how we manage acute kidney injury—and its link to chronic kidney disease.

1 Lupus nephritis (LN) is one of the most severe forms of organ ... and disease subtyping but also lay the foundation for a deeper understanding of LN pathophysiology. Moreover, through the deep ...

The US regulator has started a review of Roche's supplemental biologics license application (BLA) for Gazyva/Gazyvaro (obinutuzumab) as a treatment for lupus nephritis, with a decision expected in ...

In the following two articles, the pathophysiology, medical management, and nursing care of patients are discussed. An in-depth model care plan illustrates the complexity of the disease and its ...

Approval in lupus nephritis is expected to push the product above the $1 billion threshold and into blockbuster sales territory. Lupus nephritis is a severe form of SLE that can lead to late-stage ...

Background Tacrolimus, mycophenolate mofetil (MMF), and azathioprine (AZA) have all shown considerable effectiveness as maintenance therapy for lupus nephritis in randomized controlled trials (RCTs), ...

Background Long-term immunosuppressive treatment does not efficiently prevent relapses of lupus nephritis (LN). This investigator-initiated randomised trial tested whether mycophenolate mofetil (MMF) ...

Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern. The disease affects approximately ...

Objective To assess the efficacy and safety of the type I interferon receptor antibody, anifrolumab, in patients with active, biopsy-proven, Class III/IV lupus nephritis. Methods This phase II ...

Functional dyspepsia is a symptom complex characterised by postprandial upper abdominal discomfort or pain, early satiety, nausea, vomiting, abdominal distension, bloating, and anorexia in the absence ...

We present two cases where adult patients with IgA vasculitis (IgAV) nephritis were successfully treated with Telitacicept, experienced no adverse reactions during the follow-up. Therefore, ...

St George's Hospital Medical School, Histopathology Department, London, UK Professor M J Davies, St George's Hospital Medical School, Histopathology Department, Cranmer Terrace, London SW17 0RE, UK If ...