Terence M. Williams, MD, PhD, discussed the phase 1 DINOMITE trial of radiation therapy and papaverine in rectal cancer at ...

In the majority of cases, systemic metastases were observed without LR, confirming that metastases are a key challenge in rectal cancer treatment and not the risk of LR. Total neoadjuvant therapy (TNT ...

For example, patients who fail to achieve a pCR on neoadjuvant therapy are often considered for (more aggressive ... 28,29 In conclusion, we suggest that early response assessment in neoadjuvant ...

The addition of olaparib to neoadjuvant ... breast cancer," she told MedPage Today. "Currently, however, these patients would be receiving immunotherapy as part of their neoadjuvant therapy ...

In arm 1 of the trial, the dose-escalation portion, patients will receive mRNA-4106 at a test dose as monotherapy. In arm 2, ...

“In all the patients who had a clinical complete response, organs were preserved without additional therapy. Three patients who had rectal cancer were subsequently able to conceive and deliver ...

Patients with certain types of early-stage cancer, particularly those ... approaches and clinical trials in the neoadjuvant setting, where effective therapy can lead to responses, preserve organs ...

A new trial of patients with advanced rectal cancer has found that the addition of immunotherapy treatment alongside extended radiotherapy led to better rates of remission. The findings from the ...