Although similar alterations in NMDA receptors were detected, the differences between species underscore the need for studies on human tissue to better understand the disease.

Figure 2. Demonstration of N -methyl- D -aspartate receptor antibodies in the patient's cerebrospinal fluid. (A,B) Sagittal section of rat hippocampus incubated with the patient's cerebrospinal ...

Scientists at Shanghai Tech University have used the scaffold-hopping artificial intelligence model Geminimol to identify N-methyl-D-aspartate (NMDA) receptor ligands that show selectivity and ...

Neumora Therapeutics Inc. has patented NMDA receptor positive allosteric modulators reported to be useful for the treatment of autoimmune disease, infections, neurological and psychiatric disorders.

Hazwady Nazran, a singer-songwriter and music teacher, shares his road to recovery from an exceedingly rare autoimmune ...

NMDA receptor inhibitors, like MK-801 and memantine, lead to weight reduction in rats and reduced palatable food choices in rodents and non-human primates. These antagonists also inhibit binge ...

Single injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit: Nature (2023). DOI: 10.1038/s41586-023-06624-1 ...

Arialys Therapeutics' precision medicine has shown preclinical potential to address the underlying cause of anti-NMDA receptor encephalitis (ANRE), a rare brain disorder that comes with severe ...

Cambridge, Massachusetts-based Seyltx is already working on an NMDA receptor inhibitor of GluN2B in the form of its lead therapy ifenprodil, which was shown to significantly reduce coughing in a ...