This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

This valuable study investigates how stochastic and deterministic factors are integrated during cellular decision-making, particularly in situations where cells differentiate into distinct fates ...

Definitions from the field of systems biology apply to the ERBB network, which is described as a robust information-processing system, with a bow-tie structure, to which we apply principles of ...

Motor control refers to the process by which the nervous system coordinates the muscle and limbs to achieve a desired movement or set of actions. This includes the ability to anticipate, adjust ...

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