E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis.

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite ...

Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...