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In this study, we investigated changes in mitochondrial ultrastructure and its subcellular location in the green microalga Chlamydomonas reinhardtii and demonstrated the role of microtubules to ...
Conclusion Mitochondrial dynamics are pivotal in breast cancer metastasis, influencing metabolic flexibility, stemness, and therapy resistance. Targeting fission, fusion, and mitophagy offers a ...
Heart diseases are common clinical diseases, such as cardiac fibrosis, heart failure, hypertension and arrhythmia. Globally, the incidence rate and mortality ...
2 Mitophagy receptors Mitophagy is a specialized type of autophagy that selectively removes damaged mitochondria by linking mitochondrial components to the autophagic machinery (Pickles et al., 2018).
Mitochondrial DNA: a promising tool for characterising the population of the Tiúba stingless bee, Melipona fasciculata (Apidae, Meliponini) DNA mitocondrial: uma ferramenta promissora para ...
Our study identifies a role of UBR4 in regulating mitochondrial quality, cellular aging, and tumor growth in lung adenocarcinoma (LUAD). UBR4 enables mitophagy to maintain healthy mitochondria and ...
A complex regulatory network is known to promote functional exhaustion of CD8 + T-cells, but less is known about those factors that protect CD8 + T-cells from exhaustion. This study identifies the ...
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Mitochondrial dysfunction caused by aging leads to decreased energy metabolism, resulting in functional decline and increased frailty in multiple tissues. Strategies for protecting and activating ...