Conclusion Mitochondrial dynamics are pivotal in breast cancer metastasis, influencing metabolic flexibility, stemness, and therapy resistance. Targeting fission, fusion, and mitophagy offers a ...

By targeting TUFM-mediated mitophagy, DMF offers a method to restore mitochondrial health, reduce oxidative damage, and rebalance immune responses in periodontal tissue.

Mitochondrial cristae remain dynamic structures in order to adapt various physiopathologic processes (e.g., mitophagy and ferroptosis); thus, visualizing and tracking different changes of cristae are ...

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway. Mitophagy is an essential part of mitochondrial quality control and ...

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA).

Impact of urolithin A supplementation, a mitophagy activator on mitochondrial health of immune cells (MitoIMMUNE): A randomized, double-blind, placebo-controlled trial in healthy adults.

Mitochondrial diseases refers to a group of conditions that affect how the mitochondria of the cells produce energy. Several types exist. Learn more here.

Mitochondrial dynamics (fusion and fission) and mitophagy, are critical to mitochondrial function. Fusion allows organelles to share metabolites, proteins, and mitochondrial DNA, promoting ...

Rationale: Obesity-associated cardiomyopathy characterized by hypertrophy and mitochondrial dysfunction. Mitochondrial quality control mechanisms, including mitophagy, are essential for the ...

Rationale: Obesity-associated cardiomyopathy characterized by hypertrophy and mitochondrial dysfunction. Mitochondrial quality control mechanisms, including mitophagy, are essential for the ...

RNA-Binding Proteins Implicated in Mitochondrial Damage and Mitophagy Stylianos Ravanidis Epaminondas Doxakis * Center of Basic Research, Biomedical Research Foundation, Academy of Athens, Athens, ...