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Insilico plans late-stage trials for rentosertib following positive mid-stage safety and efficacy data for idiopathic ...

Bosakitug is a Potential Best-in-Class Investigational Monoclonal Antibody with Demonstrated Superior Potency, Residence Time ...

Disclaimer: AlphaGalileo is not responsible for the accuracy of content posted to AlphaGalileo by contributing institutions ...

Researchers at Sichuan University uncover the evolutionary links and diversity of bacterial PP2C phosphatases, key enzymes ...

Data generated from primary murine hepatocytes of healthy and WD mice and from patient-derived primary human hepatocytes were used to calibrate a dynamic pathway model of HGF-induced signal ...

The cloning of the receptor for IL-7 allows for studies to identify additional IL-7-responsive cell types, as well as to study its mechanism of signal transduction. Many references to this paper ...

While the precise mechanism of signal transduction is not known, we believe that extracellular signal is transmitted through the cytoplasm and into the nucleus, where it can result in the ...

Additionally, the precise mechanism of signal transduction is not yet fully understood. In this study, researchers utilized cryo-electron microscopy to observe the complex structure of ET ...

and the signal transduction efficiency is amplified. The specific RET fusion–related signal niche elucidates the mechanism of the constitutive activation of the Ras/MAPK signaling pathway. Beyond just ...

Their findings have recently been published in Signal Transduction and Targeted Therapy ... in their efforts to delineate the pathogenic mechanism of CR-hvKP and devise effective intervention ...