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Bilateral eye pain, redness and itching occurred after onset of rash and subsided with resolution ... activity along with downregulation of mast cell receptors results in resolution of IgE/IgG ...

These skin manifestations sometimes provide the most visible evidence of mast cell dysfunction, though they may be absent in some patients whose symptoms predominate in other body systems.

underscoring the importance of treating patients early in the ISM disease course -- -- BLU-808 healthy volunteer trial results demonstrate wide therapeutic window for modulating mast cell activity ...

For example, you may have a rash, itching ... mast cell disorder where too many abnormal mast cells (a type of white blood cell) build up in your skin and other organs. What are some common ...

Scratching worsens rashes by intensifying inflammation through nerve and immune cell interactions. Though it helps fight bacteria, the damage outweighs the benefits. Scratching an itchy rash worsens .

Yet, as most of us know, scratching a mosquito bite or a skin rash always makes it worse ... research team to continue down the path of mast-cell research, specifically the way in which new ...

If you love to scratch an itchy rash ... substance P activates mast cells through a second pathway, so the reason that scratching triggers more inflammation in the skin is because mast cells ...

Allergic contact dermatitis is an allergic reaction to allergens or skin irritants—such as poison ivy or certain metals, for example, nickel—leading to an itchy, swollen rash. Succumbing to ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a new study. A new approach to treat rosacea and other inflammatory skin conditions ...

In a previous Cell paper, Kaplan and his team found that neurons in the skin release a neurotransmitter called glutamate that suppresses mast cells. When they deleted these neurons or inhibited ...