The itch from bug bites, rashes, and other skin conditions can sometimes be so overpowering that it feels impossible to avoid ...

Scratching an itchy rash worsens inflammation by triggering pain-sensing neurons and activating mast cells, creating a ...

Additional work indicated that the act of scratching causes neurons that sense pain to secrete a molecule called substance P, which activates immune cells called mast cells. Mast cells can recruit ...

and rashes." I was curious as to how Caroline figured out the only two foods that wouldn't cause her to have this type of reaction. She said, "I was hospitalized for a mast cell flare-up in the ...

Mice that were free to scratch their itchy ears saw the number of immune cells go up and levels of infection-causing bacteria ...

That irresistible relief from scratching an itchy rash comes from the mild pain it causes, which distracts the brain from the ...

In turn, substance P activates mast cells, which are key coordinators of inflammation that drive itchiness and inflammation via recruitment of neutrophils. "In contact dermatitis, mast cells are ...