An itchy rash can be frustrating, and scratching often feels like the only relief. However, new research confirms that giving in to the urge only makes inflammation worse. The study, published in ...

In a nutshell While scratching worsens allergic skin conditions like eczema by increasing inflammation, it also activates a defense mechanism against bacterial infections, particularly Staphylococcus ...

If you love to scratch an itchy rash, good news! A new study reveals scratching a rash has upsides -- along with the downsides your mom warned you about. suriya - stock.adobe.com Scratching an ...

Urticaria pigmentosa is a rash, most common in children and young adults, characterized by reddish-brown, gray, or purple lesions. Learn about its causes, symptoms, diagnosis, treatment, and more.

While mast cells can cause problems like allergic reactions, they also help shield us from pathogens. The work also showed that the microbiome of the skin can be affected by itching as well.

Systemic mastocytosis can lead to itchy skin, headaches, and more. Learn the symptoms, diagnosis, and treatments for this condition, which causes a buildup in your body of too many mast cells -- a ...

Kaplan and colleagues are now investigating new therapies for dermatitis and other skin conditions, including rosacea and urticaria, which suppress inflammation by targeting receptors on mast ...

While mast cells are involved in a wide range of inflammatory skin conditions and allergic reactions, they’re important for protecting the skin against bacteria and other pathogens.

About 10 years ago, Daniel Kaplan, a dermatologist at the University of Pittsburgh, observed that host defenses against microbial skin infections required the involvement of the nervous system.“We ...

These skin manifestations sometimes provide the most visible evidence of mast cell dysfunction, though they may be absent in some patients whose symptoms predominate in other body systems ...

Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

IN the skin of mice painted with chemical carcinogens a remarkable accumulation of mast cells is usually observed in the altered dermis. Cramer and Simpson1 first observed that the accumulating ...