Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

Neutrophil granulocytes, a type of immune cell, are indispensable for the defense against pathogens. However, if they migrate into injured tissue, for example into the brain after a stroke, they can ...

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...

to assess the contribution of HDM protease activity to its adjuvant potential. Results: Both HDM and iHDM enhanced allergic responses to EW proteins via the oral route, evidenced by mast cell ...

Emley Moor Mast, also known as Emley Moor transmitting station, is a telecommunications and broadcasting facility on Emley Moor. The station's iconic concrete tower is 1,084ft (330.4m) tall, and is ...

Mast Capital and Starwood Capital Group secured construction financing for their oceanfront luxury condo project in Miami Beach. The joint venture closed on a $390 million loan from Eldridge ...

These cells were found to promote airway inflammation through the characteristic effector molecule Granzyme K (GZMK), which is a serine protease involved in inflammatory pathway activation.

A plan to build a mobile phone mast to boost mobile phone coverage in Guernsey has been criticised. Telecoms firm Sure has submitted plans for a 12m (39ft) timber-clad mast at the Le Mont Saint ...

This study presents a valuable finding on the role of secretory leukocyte protease inhibitors (SLPI) in developing Lyme disease in mice infected with Borrelia burgdorferi. The evidence supporting the ...

A first-in-human study of Sana Biotechnology’s transplanted islet cells has shown potential as a possible treatment for type 1 diabetes, enabling an enrolled patients to avoid immune rejection and ...