This is a well-written study that presents a solid genetic screen to identify regulators of adipose morphology and remodeling in zebrafish. The authors generated a rigorous screening platform based on ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Subscribe to our newsletter for the latest sci-tech news updates. Mucosal mast cells are immune cells that arise from bone marrow and play a key role in the sudden onset of food allergy symptoms.

An off-the-shelf stem cell therapy for type 1 diabetes continues to show positive results, according to a new study.

In breast cancer, mast cell presence is associated with a better prognosis in hormone receptor-positive tumors, whereas hepatocellular carcinoma shows the opposite trend. Therapeutic strategies aimed ...

Discover 8 ways mast cell activation syndrome causes widespread symptoms from digestive issues to brain fog, often mistaken for other conditions.

Ultimately, her research led to mast cell activation syndrome, or MCAS, a condition in which mast cells (a type of white blood cell) overreact for reasons that aren’t always clear.

A groundbreaking case study from China has shown that stem cell therapy could successfully treat type 1 diabetes, helping the body produce its own insulin.

Merck is paying $700 million upfront to buy Curon Biopharmaceutical’s bispecific antibody which depletes B cells and is being investigated for non-Hodgkin’s lymphoma and B cell acute lymphocytic ...

Mast cell activation syndrome (MCAS) is a condition where the mast cells are inappropriately triggered.