Mast cells (MCs) have the potential to secrete diverse biologically active products upon exposure to a variety of immunological or nonimmunological stimuli. Infections and inflammatory disorders ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation ... changes in matrix protease activity play an important ...

Targeting IgE with a protease ... of IgE B cell receptor. Concentration-dependent reduction of expression of the high-affinity IgE Fc receptor, on bone marrow-derived mast cells from humanized ...