Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

Mast cell activation syndrome, a disorder involving immune cells gone awry, is increasingly recognized as the culprit behind many medical mysteries. The first key to understanding this complex ...

underscoring the importance of treating patients early in the ISM disease course -- -- BLU-808 healthy volunteer trial results demonstrate wide therapeutic window for modulating mast cell activity ...

A new mobile phone mast which should see improved mobile coverge for the rural areas of North Yorkshire has been activated. The mast is the latest of the 30 Government-funded 4G upgrades across the UK ...

Depending on one's perspective, "mast cell activation syndrome (MCAS)" is either a relatively rare, narrowly defined severe allergic condition or a vastly under-recognized underlying cause of ...

body organs and/or bone marrow), mast cell cancers (for example, mast cell leukemia, mast cell sarcoma) or even the benign tumor of mastocytoma. Secondary MCAS is when the mast cells are ...

They also help maintain the function of our blood vessels (vascular homeostasis). Mast cell activation syndrome (MCAS) is a condition where the mast cells are inappropriately triggered.

A research group at the MPI of Immunobiology and Epigenetics used specialized microscopy to visualize the real-time dynamics of activated mast cells and other cell types during allergic reactions ...

Concurrent enhancer of Zeste homolog 2 (EZH2) over-expression with BRAFV600E mutation predicts a poor outcome in patients with Langerhans cell histiocytosis (LCH): A pilot study. A phase 1b/2 study of ...

Mast cell activation syndrome is a condition that causes mast cells to release an inappropriate amount of chemicals into your body. This causes allergy symptoms and a wide range of other symptoms.