Sanofi S.A. (Paris, France) and Blueprint Medicines Corp. (Blueprint), a U.S.-based, publicly traded biopharmaceutical company specializing in systemic ...

Hudson has previously said he was looking for M&A deals this year to shore up its already-strong position in immunology, ...

Sanofi to acquire Blueprint Medicines, expanding portfolio in rare immunological disease and adding early-stage pipeline in immunology ...

However, there may still be a suspicion for a clonal mast cell disorder, although it may not be as strong ... by which time your patient’s symptoms have typically resolved. This makes tryptase a ...

Systemic mastocytosis (SM) is a rare blood disorder in which the ... Each type has different symptoms, but in general, the higher the abnormal mast cell accumulation, the greater the likelihood ...

Although both conditions are diseases of mast cells and present with similar symptoms, they are different ... to rule out a primary clonal mast cell disorder as the cause. This requires further ...

Six days after the first IVIg infusion, syncope, tinnitus, anal outlet disorder and vascular spasm ... orthostatic tachycardia syndrome (POTS) and mast cell activation syndrome (MCAS) have a wide ...

Mast cell activation syndrome, a disorder involving immune cells gone ... of mast cells in the gastrointestinal tract, digestive symptoms frequently dominate the clinical picture.

Moreover, AJC structural alterations positively correlated both with mast cell activation and clinical symptoms. Conclusion The jejunal mucosa of IBS-D patients displays disrupted apical junctional ...

It's a type of mast cell disorder where too many abnormal mast cells (a type of white blood cell) build up in your skin and other organs. What are some common symptoms of systemic mastocytosis?