In BRAF-driven melanoma cells treated with BRAF inhibitors, subpopulations of cells ... progression with an increase in DNA replication stress response factors. Our findings suggest that many MAPK ...

"We're excited that the majority of gliomas demonstrated response ... BRAF inhibitors, including treatment resistance leading to disease progression and the paradoxical activation of the MAPK ...

Patients taking one of these checkpoint inhibitors in an approved indication who are experiencing an insufficient response to checkpoint ... protein kinases (MAPK) in multiple immune cell types.

Cell-survival and other stress-response messenger RNAs often contain ... the types of cancers that will respond to METTL3 inhibitors, which could help us identify the patients who will respond ...

“It could be relevant to interfere with glucose metabolism using chemical inhibitors and [to] modulate ... is required to initiate the host’s stress response to a viral infection.

In fact, selective serotonin reuptake inhibitors (SSRIs ... benefits against chronic stress. Exercise tackles inflammation by leading to an anti-inflammatory response. In addition, exercise ...