Renal failure in multiple myeloma typically occurs when the kidneys fail to filter waste products from the blood, leading to ...

Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

NF1 drug development accelerates with novel treatments aiming to surpass current MEK inhibitors in efficacy, safety, and patient-friendly delivery. The evolving NF1 landscape highlights how innovation ...

Cell-survival and other stress-response messenger RNAs often contain ... the types of cancers that will respond to METTL3 inhibitors, which could help us identify the patients who will respond ...

Key Laboratory of Application of Ecology and Environmental Protection in Plateau Wetland of Sichuan, Xichang University, Xichang 415000 Sichuan Province, China Key Laboratory of Animal Disease ...

The integrated stress response (ISR) serves as a critical adaptation mechanism ... with multiple metabolic perturbations induced by commonly used small-molecule inhibitors, we systematically studied ...

Gabby Sobelman and Myra Noveck contributed reporting. Iran’s supreme leader appeared to take a measured tone on Sunday in response to Israel’s strikes on the country, even as Iranian officials ...

Despite the availability of treatments like selective serotonin reuptake inhibitors (which increase serotonin levels ... on the specific molecular pathways directly involved in the stress response.

For example, a targeted medication might also be an immunotherapy if it works on a precise instance within the immune response (checkpoint inhibitors ... Make stress management part of your ...

were treated ex vivo with combination BRAF/MEK inhibitors dabrafenib and trametinib, and single-cell RNA sequencing (sc-RNAseq) was used to dissect the molecular features of response in differentiated ...