Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

Raman spectroscopy can be used as a tool for chemical structure analysis, chemical fingerprinting and chemical imaging. We present the demonstration of Raman spectroscopy using a SiN photonics ...

Bromodomains are protein modules that bind to acetylated lysine residues. Their interaction with histone ... Researchers at GSK also took a structure-based design approach to developing ...

8b08023 (Journal Cover) “Atomic-Scale Structure and Stress Release Mechanism in Core-Shell ... DOI: 10.1126/science.aau4146 “Understanding Chemical Bonding in Alloys and the Representation in ...

The combinatorial assembly of protein complexes is at the heart of chromatin biology. Lysine demethylase LSD1(KDM1A)/CoREST beautifully exemplifies this concept. The active site of the enzyme tightly ...

Vegetation structure was characterized in a phytosociological survey ... N ratio of leaf litter between forest fragments (FN1 and FN2) and seasons. The chemical analyses of plant tissue revealed ...