Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Knowledge Perk opened its first drive-thru in Little River in an expansion plan to grow from Rock Hill roots into a national premium coffee brand.

Country superstar Luke Bryan delivered a full moon Friday night fever set last night at a hot, sweaty and boozy sold-out Blossom Music Center.

Perks for your pet? Yes, please.Sam’s Club Just Introduced This New Member Perk and Pet Parents Will Be Thrilled originally appeared on PetHelpful. If you’re a Sam’s Club member and a proud ...

On Saturday, Mr. Trump said his administration was working with state and local officials and that Department of Homeland Security Secretary Kristi Noem would be arriving in Texas shortly. DHS ...

There's a win-win to stop complaints about fighter jet noise at Luke Air Force Base and ship the semiconductors Arizona is now producing.

Central Texas is known as 'Flash Flood Alley.' Recent floods in San Antonio, Kerrville, Austin and elsewhere a reminder of a long, tragic history of … ...

The United States and Colombia have recalled their top diplomats from their respective countries amid a deepening rift between Washington and Bogota seemingly centered on an alleged plot to oust ...

The new parents couldn't be more proud. The post The Valley’s Kristen Doute and Luke Broderick Share First Baby Photos appeared first on Reality Tea.

Salisbury organist Stephen Williams will play a holiday program of American music on Friday, July 4, at 7 p.m. at St. Luke’s Episcopal Church in downtown, Salisbury. Williams shared: “There ...

See Luke Broderick explain why he excluded Brittany Cartwright from his and Kristen Doute's engagement on The Valley After Show.

St. Luke’s Des Peres Hospital to close, laying off or transferring 336 employees, including 210 full-time, due to financial losses. Closures begin Aug. 1.