ahajournals.org3d
Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure With Exogenous MecciRNA
BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.
eLife3d
Interplay of YEATS2 and GCDH mediates histone crotonylation and drives EMT in head and neck cancer
These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...
eLife3d
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation
This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...
EurekAlert!5d
From shoot apex to flower: single-cell insights in Chinese cabbage
A new study using single-cell transcriptomics has unlocked the intricate cellular mechanisms that govern flowering and ...
The EMBO Journal12d
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
GitHub19d
A modern diagram scripting language that turns text to diagrams.
In addition to being a runnable CLI tool, D2 can also be used to produce diagrams from Go programs. For examples, see ./docs/examples/lib. This blog post also demos a complete, runnable example of ...
BBC20d
How the brain's little blue dot regulates your sleep
the neuroscience researcher and writer Mithu Storoni describes the locus coeruleus, and its control over norepinephrine signalling, as the brain's gearbox, with different modes that are best ...