Creatine may do more than boost strength - it could help protect your brain. New research links low creatine levels to Alzheimer’s and cognitive decline. Learn how this powerful supplement may ...

In the APOLLOE4 trial (ClinicalTrials.gov Identifier: NCT04770220), study participants aged 50 to 80 years with the APOE4/4 genotype (N=325) were randomly assigned to receive valiltramiprosate ...

But in the presence of the APOE4 protein-;the most important genetic risk factor for Alzheimer's disease-;the same cells cause harmful inflammation and clumps of misfolded proteins, according to a ...

Meeting Coverage > CTAD Omega-3 Supplements Show Benefit in APOE4 Carriers — Trial finds DHA can penetrate the brain before dementia onset by Judy George, Deputy Managing Editor, MedPage Today ...

Meeting Coverage > AAIC Video Pearls Finding That APOE4 Is Toxic in Alzheimer's Can Help Guide Targeted Therapies — Differing risk of APOE4 between ethnic backgrounds also may come into play by ...

That's what's at work with research into the APOE4 gene. According to a recent study released by the National Institutes of Health and published in "Nature Medicine," the disease may be more ...

By age 55, participants with two APOE4 copies were accumulating more amyloid, a protein that forms plaques in the brain that signal Alzheimer’s, than those with just one copy of another form of ...

If you have two copies of the APOE4 gene, new research suggests that you’re very likely to develop Alzheimer’s. Experts break down the findings and share what you can do to lower your risk.

A study has found that having two APOE4 genes may not just be a risk factor in Alzheimer's disease, but a driver of it. Nearly all carriers' brains showed key disease biomarkers by age 65 ...

We each inherit two copies of genes (that are not on the X and Y sex chromosomes), including APOE4, from our parents. When the two copies are identical, they are said to be homozygous. In this study, ...

The study shows that people with two copies of APOE4 “meet the three main characteristics of genetically determined [Alzheimer’s disease],” the authors write: a high prevalence of the ...

Classifying APOE4 as an inherited form of the disease has some big implications. First, it would mean that a far greater proportion of Alzheimer’s cases are caused by genes than has been ...