Many associations linking greater sedentary time with brain health and cognitive outcomes were present in APOE4 carriers but not in non-carriers, suggesting increased sedentary time may be ...

Having two copies of the ApoE4 gene is not just a risk factor for the development of Alzheimer’s, but is a likely cause of the disease, according to researchers in Spain. The finding is ...

A Medicare analysis found large disparities in which Alzheimer's patients were treated with lecanemab. Lecanemab use was higher in people who were male, white, urban, and socioeconomically ...

Nuala and Gerry Paley first met when she was 21 and he was 23. Their relationship didn’t take off properly in the beginning, but they met again eight years later and were married within six months.

At AD/PD TM 2025 in Vienna, Annovis gave two presentations, showcasing findings from its Phase 3 PD trial and data on buntanetap in ApoE4 carriers from its Phase 2/3 AD study. The Company also ...

Hypertension and dyslipidemia rates were somewhat higher than in Clarity, while diabetes was lower. Half were APOE4 heterozygotes, 8.5 percent were APOE4 homozygotes. Pretreatment counseling at WashU ...

May 29, 2025 — Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material ...

Patients with only one or no copy of ApoE4 are less likely to experience so-called ARIA side effects, like brain swelling and bleeding, associated with amyloid-targeting drugs, than people with ...