Traffic will shift on Interstate 64 in Hampton this weekend. WAVY's Julia Avery explains.

An Alton woman was left dead early Tuesday morning after a fatal single-vehicle crash on Interstate 64. According to the Missouri State Highway Patrol (MSHP), the crash took place around 12:40 a.m. on ...

RICHMOND HEIGHTS, Mo. — A woman died in a crash early Tuesday morning after her vehicle went off the road along Interstate 64. According to a crash report from the Missouri State Highway Patrol ...

The Missouri Department of Transportation (MoDOT) plans to close the ramp from westbound Interstate 64 to Boone's Crossing (Exit 17) on Thursday, July 17. Drivers who use westbound I-64 into ...

ST. LOUIS COUNTY — The preferred location for a planned new regional police training facility is the vicinity of Interstate ...

JEFFERSON CITY — Plant and tree nurseries in Missouri soon will be prohibited from selling a handful of fast-spreading ...

A state economic development fund is kicking in $20 million for a project to expand an Interstate 64 interchange that will ease traffic in New Kent county.

KANAWHA COUNTY, W.Va. (WCHS) — Evening commuters utilizing Interstate 64 East in Kanawha County were stalled Tuesday evening as crews work to clear an asphalt spill, emergency dispatchers said.

A multi-vehicle crash on Interstate 64 caused lane closures and many serious injuries, including those to a five-year-old who was ejected from a head-on collision.

A semi-truck traveling on Interstate 65 in Louisville caught fire and went over the barrier, crashing onto Interstate 64 East and Interstate 71 North below.