Traffic will shift on Interstate 64 in Hampton this weekend. WAVY's Julia Avery explains.

An Alton woman was left dead early Tuesday morning after a fatal single-vehicle crash on Interstate 64. According to the Missouri State Highway Patrol (MSHP), the crash took place around 12:40 a.m. on ...

JEFFERSON CITY — Plant and tree nurseries in Missouri soon will be prohibited from selling a handful of fast-spreading ...

The Missouri Department of Transportation (MoDOT) plans to close the ramp from westbound Interstate 64 to Boone's Crossing (Exit 17) on Thursday, July 17. Drivers who use westbound I-64 into ...

ST. LOUIS COUNTY — The preferred location for a planned new regional police training facility is the vicinity of Interstate ...

RICHMOND HEIGHTS, Mo. — A woman died in a crash early Tuesday morning after her vehicle went off the road along Interstate 64. According to a crash report from the Missouri State Highway Patrol ...

A state economic development fund is kicking in $20 million for a project to expand an Interstate 64 interchange that will ease traffic in New Kent county.

KANAWHA COUNTY, W.Va. (WCHS) — Evening commuters utilizing Interstate 64 East in Kanawha County were stalled Tuesday evening as crews work to clear an asphalt spill, emergency dispatchers said.

A semi-truck traveling on Interstate 65 in Louisville caught fire and went over the barrier, crashing onto Interstate 64 East and Interstate 71 North below.