A proof-of-concept study finds that donated insulin-producing cells can be genetically modified to avoid provoking the recipient's immune system.

For more than a hundred years, insulin has been the key to controlling type 1 diabetes. It has saved lives by preventing diabetic ketoacidosis (DKA), a life-threatening condition that happens when the ...

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell ...

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure. This review ...

Byproducts from gut bacteria breaking down tryptophan, a dietary amino acid, can restore hormone-secreting gut cells reduced ...

A decade after an overlooked discovery, researchers now confirm that the hormone leptin can reverse diabetic ketoacidosis (DKA) even without insulin.

Although metformin has been the go-to medication to manage type 2 diabetes for more than 60 years, researchers still do not ...

Insulin resistance is a hallmark of multiple metabolic disorders, including type 2 diabetes, obesity, metabolic syndrome, and polycystic ovary syndrome. It ...

University of Pennsylvania and Syracuse University scientists have discovered that a hindbrain-derived peptide, octadecaneuropeptide (ODN), can suppress appetite and improve glucose regulation without ...

Creatine supplementation may improve cognitive performance and mood, offering insights into its role in muscle-brain ...

Figure 2. Schematic representation of signaling pathways common to AD and DM induced by GLP-1R agonism. These include AMPK, PI3K/AKT, CaMKK2-AMPK, NF-κB, insulin/IGF-1 R and the mitochondrial ...

In diabetes, much attention goes to sugar control, insulin levels, and the threat of nerve damage. But a new study reveals ...