Professor Vázquez-Carrera notes, "The insulin signaling pathway is initiated when insulin binds to a receptor on the cells of insulin-responsive tissues. This receptor is composed of the α ...

Several lines of evidence link metabolic dysregulation to late-life neurodegenerative diseases. The altered glucose ...

Type 2 diabetes mellitus (T2DM) is a complex disorder that has a heterogeneous genetic and environmental background. In this Review, we discuss the role of relatively infrequent polymorphisms of ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.

Insulin is a vital hormone that controls ... such as in the so-called mTOR signaling pathway—a key regulator of cell division ...

New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD ...