Frontiers16d
A role of gut microbiota metabolites in HLA-E and NKG2 blockage immunotherapy against tumors: new insights for clinical application
One of major breakthroughs in immunotherapy against tumor is from blocking immune checkpoint molecules on tumor and reactive T cells. The development of CTLA-4 and PD-1 blockage antibodies has ...
C&EN1mon
Discovery of Peptidic Siderophore Degradation by Screening Natural Product Profiles in Marine-Derived Bacterial Mono- and Cocultures
School of Chemistry and Biochemistry, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia 30332, United States Center for Microbial Dynamics and Infection, Georgia Institute of ...
C&EN1mon
Neuroprotective Indole Alkaloids from the Soil-Derived Fungus Trichocladium sp. XZ8
Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, People’s Republic of China ...
Frontiers1y
Microbial metabolites are involved in tumorigenesis and development by regulating immune responses
In addition, Zhang et al. recently found that indole-3-lactic acid, a metabolite of Lactobacillus plantarum L168, could ameliorate intestinal dysbiosis and inhibit tumor growth in a mouse model of ...