Lipid nanoparticle platform delivers mRNA to the brain
A well-known in vitro model of the blood-brain barrier that is widely used in studies of neurodegenerative diseases and in preclinical research is made from the wrong kind of cells, according ...
A 3D model accurately mimicking the Blood-Brain Barrier (BBB) in a laboratory environment has been successfully developed by research teams led by Professor Jinah Jang from the Departments of ...
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Innovative 3D blood-brain barrier model enhances understanding of neuroinflammationA 3D model accurately mimicking the Blood-Brain Barrier (BBB) in a laboratory environment has been successfully developed by research teams led by Professor Jinah Jang from the Departments of ...
In contrast, blood vessel organoids did not express these molecules before integrating into the cerebral organoids. To assess the barrier ... brain,” he said. This is particularly important ...
Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier. In research published in Fluids and Barriers of the CNS, ...
glial cells and the blood-brain barrier following ischemic insult. We also describe the evidence of TRPM2 involvement in these processes, as shown from numerous in vitro and in vivo studies that ...
Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...
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