The concept of IgG4-related disease was introduced in 2011 (6), and now encompasses a number of conditions previously regarded as isolated, idiopathic entities, including autoimmune pancreatitis, ...

Unlike most autoimmune conditions, AIP has a male predominance, with a male:female ratio of 2:1. [29,32,33] The peak age of onset is the sixth and seventh decade.[29,32,33] Early data suggest that ...

Introduction. Autoimmune pancreatitis (AIP) is a disease that is being increasingly recognized as a distinct clinical entity worldwide. While Sarles et al. may have been the first to describe the ...

El-Reshaid, K. and Al-Bader, A. (2025) Acute Autoimmune Pancreatitis and Interstitial Nephritis, due to IgG4 Disease, Following Pfizer-BioNTech COVID-19 Vaccination —IgG4 Disease Following COVID-19 ...

“For the first time, we have a drug that is not only approved for IgG4-related disease, but works best in the GI manifestations of the disease, including autoimmune pancreatitis and immune ...

INTRODUCTION. Immunoglobulin G4 (IgG4)-related disease is a systemic autoimmune disease with pancreatic and extrapancreatic abdominal manifestations; it can affect the bile ducts, kidneys, lymph nodes ...

Eighty-one patients with IgG4-RD took part in the study. The most common clinical features in this cohort of patients included respiratory disease (23.5%), autoimmune pancreatitis (22.2%), and Riedel ...

Immunoglobulin G4-related disease (IgG4-RD) is a rare inflammatory disorder that can affect various organs in the body, with symptoms typically manifesting based on the affected area. It has only been ...

For instance, conditions like Riedel’s thyroiditis, once thought to be an isolated inflammatory disorder of the thyroid gland, were able to be seen as part of the broader IgG4-RD spectrum. Similarly, ...

An imbalance in specific antibodies can be a sign of autoimmune disease. High levels of IgG4, a particular type of antibody, can lead to widespread organ damage and mass growth.

Report 02 cases of IgG4 disease with renal manifestations revealing the disease such as extramembranous glomerulonephritis and tubulointerstitial nephritis rich in polytypic IgG4+ plasma cells.