Clinicians should consider IgG4-related sclerosing disease in the differential diagnosis to avoid unnecessary surgery. Autoimmune pancreatitis (AIP) should be diagnosed on the basis of a ...

Although elevated serum IgG4 levels have been linked ... Inflammatory bowel disease is frequently associated with autoimmune pancreatitis. In one series, 9 of 53 patients (17%) with autoimmune ...

These radiologic findings correspond to autoimmune pancreatitis and tubulointerstitial nephritis, with histopathological and immunohistochemical-staining features of IgG4-related disease.

“Defined about 30 years ago, autoimmune pancreatitis [AIP] remains ... linked to immunoglobulin G4–related disease (IgG4-RD), and type 2 AIP, primarily associated with inflammatory bowel ...

I suppose the chief characteristic really is that it is so indolent compared to many other autoimmune ... Even pancreatitis, one of the most concerning manifestations of IgG4-related disease ...

Autoimmune pancreatitis (AIP ... called IgG4-related disease (IgG4-RD). When induced repeatedly with polyinosinic-polycytidylic acid (poly(I:C)), murine models of AIP (MRL/MpJ mice) were similar ...

“For the first time, we have a drug that is not only approved for IgG4-related disease, but works best in the GI manifestations of the disease, including autoimmune pancreatitis and immune ...

Type 2 is less common and has nothing to do with IgG4. If you have ... one has been diagnosed with autoimmune pancreatitis. In fact, it is estimated that the disease affects about 1 in 100,000 ...

IgG4-related disease is a multifaceted, systemic fibroinflammatory condition that can affect virtually any organ, with autoimmune pancreatitis representing one of its most well‐characterised ...

IgG4 either cannot be detected or is found at very low levels. This type of autoimmune pancreatitis is also sometimes associated with inflammatory bowel disease (IBD). Type 2 disease appears to ...

More information: Akane Hara et al, A positive cytokine/chemokine feedback loop establishes plasmacytoid dendritic ...