Interleukin (IL)-1 is a prototypic proinflammatory cytokine. It is produced by numerous cell types (i.e., macrophages, synoviocytes, endothelial cells, chondrocytes, osteoclasts) and is found in ...

The first direct and selective interleukin-1 (IL-1) receptor antagonist, anakinra can be used alone or in combination with any of the other DMARDs, except those in the tumor necrosis factor (TNF ...

genes were first cloned and characterized as the sixth IL-1 receptor (IL-1R1). Three receptor activating cytokines (IL-36α, IL-36β, IL-36γ) and one antagonist (IL-36Ra) were identified in quick ...

SAN DIEGO -- Patients with moderate to severe ulcerative colitis experienced clinical, endoscopic, histological, and biological improvements with the first-in-class interleukin (IL)-7 receptor ...

(UroToday.com) The 2025 American Society of Clinical Oncology (ASCO) Annual Meeting held in Chicago, IL between May 30 and June 3 was host to the Poster Session: Genitourinary Cancer - Prostate, ...