Focal potassium microinjection induces the incidence of epileptiform activities of rat hippocampal slices. We investigated the seizure responses of this activity in vitro using extracellular records ...

Braz J Med Biol Res, July 2006, Volume 39 (7) 915-924 Assessment of the progressive nature of cell damage in the pilocarpine model of epilepsy L. Covolan and L.E. Mello Departamento de Fisiologia, ...

Occurrence of seizure in some Alzheimer's disease (AD) patients suggests that the mechanisms involved in pathology of AD may also give rise to occurrence of neural hyperexcitability. Among the ...

Although the function of the p42/p44 mitogen-activated protein (MAP) kinase pathway in long-term potentiation at hippocampal CA3–CA1 synapses has been well described, relatively little is known ...