A new generation of drugs called protease inhibitors, when combined with other drugs, made the virus virtually undetectable in people with HIV, giving them a much greater chance of living to old age.

At this point, the efficacy of the CCR5 inhibitor maraviroc is uncertain, while protease inhibitors have variable efficacy in people with HIV-2, with lopinavir and darunavir being the most useful.

Then, in 1985, Abbott launched the world's first HIV antibody assay. In 1996, one of the first protease inhibitor drugs indicated in combination with other antiretroviral agents for the treatment ...

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although data on HIV-2 prevalence are generally more limited.4 5 Regarding antiretroviral therapy, although indinavir is an example of the protease inhibitor class, it has been avoided for more than a ...

Methods: The GOLD 5.0 molecular docking program was used to dock 20 HIV and HCV drugs against the ZIKV protease. Based on docking scores, 5 drugs were found to bind to the ZIKV protease with high ...

This proof-of-concept study highlights the feasibility of long-acting protease inhibitors for HIV treatment, though refinement is needed before clinical application. While TLC-ART 101 will not ...

Some drugs can impair liver function and cause high bilirubin levels. Certain protease inhibitors used to treat human immunodeficiency virus (HIV) and targeted therapies like Nexavar (sorafenib), used ...

In drastically cutting down its public health workforce, the Trump administration is potentially undoing decades of work combatting the HIV epidemic and delaying upcoming advances. When Health and ...

Advocates and state officials gathered on the steps of the state Capitol on a warm spring Tuesday to commemorate Connecticut’s 25th annual HIV/AIDS Awareness Day. The event — part celebration ...

The Trump administration is potentially undoing decades of work to mitigate the HIV epidemic and holding up upcoming progress by slashing the country’s public health workforce, experts say.