Roche is moving its novel antibiotic zosurabalpin into phase 3 testing for carbapenem-resistant Acinetobacter baumannii (CRAB), a 'superbug' that is considered an 'urgent threat' by the CDC, in what ...

Microbiology is all about studying the tiny world of germs, bacteria, viruses, and more. Scientists use abbreviations to keep ...

while also decreasing levels of Gram-negative bacteria that produce inflammatory compounds like lipopolysaccharides (LPS). These changes could have systemic anti-inflammatory effects—benefitting ...

Gram-negative bacteria, such as E. coli, are common culprits in sepsis because they release LPS when they invade the bloodstream. These antibodies, created at OHSU, have already been tested in early ...

Gram-negative bacteria, such as E. coli, are common culprits in sepsis because they release LPS when they invade the bloodstream. "Sepsis can be incredibly challenging to treat," said Joseph Shatzel, ...

One subset of pyrogens are lipopolysaccharides (LPS), also called endotoxins. These glycolipids, found in the outer membrane of gram-negative bacteria, comprise lipid A, a core oligosaccharide ...

Bacteria that have an additional protective layer to their cell walls - a type known as "Gram-negative" in reference to the staining ... protective layer is a molecule called lipopolysaccharide (LPS).

The new compounds target a protein, LpxH, which is used by Gram-negative bacteria in a pathway to synthesize lipopolysaccharide (LPS), a structural component in the outer membrane (OM) of the ...

According to The Guardian, the new drug focuses on the LPS barrier that allows gram-negative bacteria to live in any environment and easily resist antibiotics. The newspaper cited experts who ...

LPS is made inside the bacterial cell and ... antibiotic was launched that is capable of treating infections by Gram-negative bacteria,” he said in an email. “Any new antibiotic class that ...