In a landmark discovery, researchers have unveiled the highly dynamic and adaptable architecture of the mammalian pyruvate ...

MIT researchers found that high-fat diets cause metabolic enzyme dysfunction and insulin resistance by increasing reactive ...

Researchers find high-fat diets set off metabolic dysfunction in cells, leading to weight gain, but these effects can be ...

N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ)-are raising new red flags for aquatic ecosystems.

Prior research has linked both chemicals to developmental and systemic toxicity in aquatic organisms, but the mechanisms behind their long-term effects—particularly on liver function and neurobehavior ...

"Creative Proteomics has worked with over a dozen pharmaceutical clients to identify new targets in glycolysis-dependent cancers and validate mechanism-of-action for drugs targeting metabolic enzymes ...

Some of these enzymes could also be good targets for new malaria drugs. “Plasmodium falciparum relies heavily on free energy produced during glycolysis for its survival, growth and replication.