However, when the researchers blocked an earlier step in glycolysis, the enzyme glucose-6-phosphate isomerase, this had no effect on the growth of the cancer cells. "The glycolytic enzyme aldolase ...

This makes the results published by Almut Schulze and colleagues from the German Cancer Research Center (DKFZ) all the more surprising: when the researchers blocked the enzyme aldolase A, which ...

Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice and humans depend on a key enzyme of glycolysis, Aldolase A. When it is switched off ...

GENFI Top Hits. CSF proteomics linked abundance of CALB2, GRN/NAGA, and PEA15/SEMA6A to C9ORF72 (gold), GRN (red), and MAPT ...

and even how cells break down sugar to create energy (a process known as glycolysis). There is only one enzyme capable of attaching a sugar to the proteins that reside inside the cell, and it is ...

The study links exertional heat stroke to chronic disorders, revealing impacts on body mass regulation and heart health, ...

Here, we demonstrate that glycolytic enzyme hexokinase 2 (HK2) plays a crucial role in upregulating PD-L1 expression. Under high glucose conditions, HK2 acts as a protein kinase and phosphorylates ...

Here, we report that the glycolytic enzyme phosphoglycerate mutase (PGAM), which converts 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG), is physiologically upregulated in Tregs and its ...