News Medical on MSN6d
Lactate dehydrogenase activity in rat tissues under intermittent hypobaric hypoxia
Announcing a new article publication for BIO Integration journal. As altitude increases, the partial pressure of oxygen will ...
ALZFORUM1d
Proteomics Lays Groundwork for FTD Biomarkers
GENFI Top Hits. CSF proteomics linked abundance of CALB2, GRN/NAGA, and PEA15/SEMA6A to C9ORF72 (gold), GRN (red), and MAPT ...
Weakness in lung cancer's defenses found—an enzyme that boosts cancer cell metabolism
Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, ...
The EMBO Journal6d
Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile
In patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting ...
Too Old to Operate5d
Impact of Dupilumab on Skin Protein and Metabolite Composition in AD
The following is a summary of “Longitudinal integrated proteomic and metabolomic skin changes in atopic dermatitis patients ...
BMJ4d
L-arginine metabolism inhibits arthritis and inflammatory bone loss
RNA-seq and MS analyses indicated that L-arginine switched glycolysis to oxidative phosphorylation in inflammatory osteoclasts leading to increased ATP production, purine metabolism and elevated ...
BBC4d
Effect of pH on enzyme activity
pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...