Abstract: Within the field of protein structure prediction, the packing of alpha-helical proteins has been one of the more difficult problems. Distance constraints and topology predictions can be ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein ...

David Baker, Demis Hassabis and John M. Jumper shared the Nobel Prize in Chemistry on Wednesday for their work on protein structure. Atila Altuntas / Anadolu via Getty Images On Wednesday morning ...

Areas of a protein structure colored blue indicate high confidence, while red areas show less certainty. Baker adds that it is a shame that the source code for AlphaFold 3 has not been released to ...

or M protein, is the most abundant and plays a crucial role in how the virus acquires its spherical structure. Nonetheless, this protein's properties are not well understood. A research team led ...

A Virus Lookalike To figure out how PNMA2 kickstarts an immune reaction, Junjie Xu, a graduate researcher in neurobiology at U of U Health and the lead author on the study, examined the protein’s ...

Extended, coiled-coil conformation is likely to permit protein “packing” in the secretory granule at ∼50% higher density than a globular/spherical conformation ... new roles for secretory protein ...

Protein structure is so important that there's an entire discipline, along with several well-developed approaches, to figuring out what a protein looks like when it's all folded up into its active ...

In a recent study by the team, they discovered the 3D structure of a protein called TnpB, a probable precursor to the CRISPR-Cas12 enzyme. Their findings appeared in the journal Nature.

The tertiary structure of a protein is its overall shape ... Generally, proteins can be divided into four classes regarding their global shape: globular proteins, fibrous proteins, membrane proteins ...

However, developing an HCV vaccine based on that protein is limited by uncertainty around what it looks like. Knowing the structure of the protein is necessary to figure out how the immune system ...