Novo Nordisk A/S’s next-generation obesity shot CagriSema helped patients lose weight in large studies despite only about three-quarters of the patients ever making it to the highest dose.

1905 — Christy Mathewson of the New York Giants pitched his second no-hit game, beating the Chicago Cubs and Mordecai Brown 1-0 ... 1973 — The Los Angeles Dodgers’ infield of Steve Garvey (first base) ...

The city of Chicago is just one week away from NASCAR’s top drivers speeding through Grant Park, and significant street closures are on the way.

NBC Chicago’s Christian Farr reports. Preparations are underway for the NASCAR Chicago Street Race, but the biggest street closures are set to go into effect in coming hours.

Here's a look back at what happened in the Chicago area on June 14, according to the Tribune's archives.

The Chicago Board of Education on Wednesday approved Macquline King as interim schools chief, replacing outgoing CEO Pedro Martinez as the search for a permanent leader continues.

Chicago public schools face enrollment crisis with 150 half-empty schools, costing up to $93,000 per student in some cases, as the district lost 70,000 students over the past decade.

The 2025 NASCAR Chicago Street Race has finally arrived, with the world’s best stock car drivers bringing their talents to the Windy City. Both the Xfinity Series and the Cup Series will take on ...

Shane van Gisbergen has completed a sweep on the Chicago Street Course, winning the NASCAR Cup Series race on the tricky ...

Here’s a look back at what happened in the Chicago area on June 13, according to the Tribune’s archives. Is an important event missing from this date? Email us. Weather records (from the ...

High school basketball classics abounded in western Cook County Proviso East, St. Joseph’s representation expected, but that doesn’t make these selections any easier.

But no one from the Chicago area saw it; they just heard about it. But make no mistake, the 2,000-plus-point scorer was a gifted all-around player at 6-8 and one of the nation’s best prep stars.