The researchers changed the expression of two kinds of GABA receptors to figure out if receptor density had any impact on synchrony or behavior. "Tuning the number of receptors is considered to be ...

The researchers changed the expression of two kinds of GABA receptors to figure out if receptor density had any impact on synchrony or behavior. "Tuning the number of receptors is considered to be ...

SAN DIEGO--(BUSINESS WIRE)--Lassen Therapeutics, a clinical stage biotechnology company developing first-in-class antibody therapeutics targeting interleukin-11 receptor (IL-11R; LASN01 ...

A poster entitled “LASN01, a high affinity anti-interleukin-11 receptor antibody, blocks pathological mechanisms of thyroid eye disease linked to clinical efficacy” described how LASN01 inhibits ...

Scientists have revealed the molecular structure of a type of receptor that's crucial to brain development and function. 'This study shows the dominant assemblies and states of the GABA receptor.

We report the successful use of RZ358, a novel human anti–insulin receptor monoclonal antibody, in a patient with metastatic insulinoma in whom severe, refractory hypoglycemia developed after ...

EGRET: A first-in-human study of the novel antibody-drug conjugate (ADC) AZD9592 as monotherapy or combined with other anticancer agents in patients (pts) with advanced solid tumors. This is an ASCO ...

The new report suggests patients with acetylcholine receptor (AChR) antibody titers above 8.11 nmol/L were at higher risk of conversion. Antibody titers in patients with acetylcholine receptor ...

“These studies are an important reminder to interpret antibody-dependent data carefully and that ... α-synuclein phosphorylation responded to neuron signaling. He used the GABA receptor antagonist ...

The company’s lead candidate is LASN01, a best-in-class monoclonal antibody targeting IL-11 receptor (IL-11R). IL-11, a member of the IL-6 family of cytokines, is a central mediator of fibrosis ...

Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with ...