Although G protein-coupled receptors (GPCRs) are crucial to the regulation of most functions in the human body, very little is known about how they work. In a new study, researchers at the Biozentrum ...

The discovery of G protein-coupled receptor (GPCR) heteromers has revealed a new level of complexity in their functional characteristics. This review explores a variety of methodologies and live ...

A newly discovered receptor switch that boosts bone growth could transform how we treat osteoporosis, by stimulating the body ...

BOSTON, July 16, 2025 /PRNewswire/ -- According to the latest study from BCC Research, the " G-Protein Coupled Receptor (GPCR) Targeting: Technologies and Global Markets " is expected to grow from ...

Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic ...

In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain. Subscribe to our ...

Cystic fibrosis is a life-threatening disease predominantly with respiratory symptoms. Most of the subjects with the disease harbor the F508del variant in the CFTR gene that causes the protein to ...

Agonists to the μ-opioid G protein-coupled receptor (μOR) can alleviate pain through activation of G protein signaling, but they can also induce β-arrestin activation, leading to such side effects as ...

Wikimedia Commons, Valeryns The 2012 Nobel Prize for Chemistry goes to Robert J. Lefkowitz of Duke University and Brian K. Kobilka of Stanford University for their work in discovering the inner ...

G protein–coupled receptor, family C, group 5, member D (GPRC5D) is an orphan receptor expressed in malignant plasma cells. Talquetamab, a bispecific antibody against CD3 and GPRC5D, redirects T ...